Journal: iScience

Article Title: A sustainable and regioselective synthesis of Hemi-bis(monoacylglycero)phosphates and bis(diacylglycero)phosphates

doi: 10.1016/j.isci.2023.107075

Figure Lengend Snippet: Hemi-bis(monoacylglycero)phosphate and Bis(diacylglycero)phosphate production

Article Snippet: Monopalmitin (Racemic mixture) , Dupont Danisco , Cas # 26657-96-5.

Techniques:

Journal: iScience

Article Title: A sustainable and regioselective synthesis of Hemi-bis(monoacylglycero)phosphates and bis(diacylglycero)phosphates

doi: 10.1016/j.isci.2023.107075

Figure Lengend Snippet: Overview substrate affinity docking models Illustrates the substrate affinity and docking models of phospholipase D for 1-palmitoyl-2-oleoyl- sn -glycero-phosphatidylcholine (POPC) and various alcohol donors (racemic mixtures), with the side chains of the POPC excluded, R 1 (blue) and R 2 (red). Vmax and Km are presented with the binding distances between the phosphate and the specific alcohol donor, in regard to the catalytic active histidine groups (His170 and His 448). (A) Overall ribbon structure of phospholipase D (Streptomyces sp .). (B) Monolaurin. (C) Monopalmitin. (D) Monoolein. (E and F) Monodocosaoin and F: Distearin.

Article Snippet: Monopalmitin (Racemic mixture) , Dupont Danisco , Cas # 26657-96-5.

Techniques: Binding Assay

Journal: Molecules

Article Title: Quantitative Analysis of Cenobamate and Concomitant Anti-Seizure Medications in Human Plasma via Ultra-High Performance Liquid Chromatography–Tandem Mass Spectrometry

doi: 10.3390/molecules29040884

Figure Lengend Snippet: Comparison of existing analytical methods for the quantification of CNB in LC-MS/MS. EDTA = ethylenediamine tetraacetic acid; AcN = acetonitrile; MeOH = methanol; APCI = atmospheric pressure chemical ionization; ESI = electrospray ionization.

Article Snippet: Cenobamate (racemic mixture) was purchased from Alsachim (Illkirch, France).

Techniques: Comparison, Extraction, Mass Spectrometry, Clinical Proteomics, Targeted Proteomics, Evaporation

Journal: Molecules

Article Title: Quantitative Analysis of Cenobamate and Concomitant Anti-Seizure Medications in Human Plasma via Ultra-High Performance Liquid Chromatography–Tandem Mass Spectrometry

doi: 10.3390/molecules29040884

Figure Lengend Snippet: Summary of patients’ data used for method comparison ( n = 47, samples n = 99).

Article Snippet: Cenobamate (racemic mixture) was purchased from Alsachim (Illkirch, France).

Techniques: Comparison, Clinical Proteomics, Concentration Assay

Journal: iScience

Article Title: A sustainable and regioselective synthesis of Hemi-bis(monoacylglycero)phosphates and bis(diacylglycero)phosphates

doi: 10.1016/j.isci.2023.107075

Figure Lengend Snippet: Hemi-bis(monoacylglycero)phosphate and Bis(diacylglycero)phosphate production

Article Snippet: Distearin (Racemic mixture) , Dupont Danisco , Cas # 1323-83-7.

Techniques:

Journal: iScience

Article Title: A sustainable and regioselective synthesis of Hemi-bis(monoacylglycero)phosphates and bis(diacylglycero)phosphates

doi: 10.1016/j.isci.2023.107075

Figure Lengend Snippet: Overview substrate affinity docking models Illustrates the substrate affinity and docking models of phospholipase D for 1-palmitoyl-2-oleoyl- sn -glycero-phosphatidylcholine (POPC) and various alcohol donors (racemic mixtures), with the side chains of the POPC excluded, R 1 (blue) and R 2 (red). Vmax and Km are presented with the binding distances between the phosphate and the specific alcohol donor, in regard to the catalytic active histidine groups (His170 and His 448). (A) Overall ribbon structure of phospholipase D (Streptomyces sp .). (B) Monolaurin. (C) Monopalmitin. (D) Monoolein. (E and F) Monodocosaoin and F: Distearin.

Article Snippet: Distearin (Racemic mixture) , Dupont Danisco , Cas # 1323-83-7.

Techniques: Binding Assay